Public Health hopes it was an unusual surge in cases.
Ten new cases were reported in Niagara on Saturday, and then another three yesterday.
There are 35 active cases, with the highest number in Lincoln.
That's followed by Pelham, Niagara Falls, and Thorold.
There are active cases in seven municipalities in the Region.
Nearly 88 per cent of people with the virus in Niagara have recovered.
There are still no patients with COVID-19 in local hospitals.
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